pdfSetTIFFBigMode

Enable or disable 'BigTIFF' mode for TIFF output.
void pdfSetTIFFBigMode(PDFHandle pdf, int big)
This function enables (if big is non-zero) or disables (if big is zero) use of BigTIFF mode when generating a TIFF file. BigTIFF is a standard TIFF extension that uses 64-bit offsets, allowing TIFF files larger than 4GB.

The pdfResetBitmapParams function resets BigTIFF to the default value of disabled.

C:
pdfSetTIFFBigMode(pdf, 1);
pdfResetBitmapParams
pdfWritePageBitmap
pdfWriteRegionBitmap